RecallRadar

FDA Device recall Z-1277-2016

Estradiol II Elecsys and cobas e analyzers REF 03000079 190

On 2016-04-06 the FDA classified a Class II recall of Estradiol II Elecsys and cobas e analyzers REF 03000079 190 by Roche Diagnostics Operations, citing due to the risk of a recently identified cross reactivity, the Elecsys Estradiol assay should not be used when monitoring patient being treated with fulvestrant. Customers should….

Read the official FDA Device notice

AgencyFDA Device
Recall numberZ-1277-2016
ClassificationClass II
Statusterminated
Initiated2016-03-07
Published2016-04-06
Last updated2026-09-13 11:54 UTC
CompanyRoche Diagnostics Operations
DistributionUS

Product

Estradiol II Elecsys and cobas e analyzers REF 03000079 190; M 6.5mL, R1 8 mL, R2 8 mL, IVD, For USA: CONTENT M Streptavidin-coated microparticles 0.72 mg/mL; R1 Biotinylated polyclonal anti-estradiol antibody (rabbit) 45 ng/mL; Mesterolone 130 ng/mL; R2 Estradiol derivative, labeled with ruthenium complex 2.75 ng/mL Product Usage: Immunoassay for the in vitro quantitative determination of estradiol in human serum and plasma. The electrochemiluminescence immunoassay ECLIA is intended for use on Elecsys and cobas e immunoassay analyzers.

Reason

Due to the risk of a recently identified cross reactivity, the Elecsys Estradiol assay should not be used when monitoring patient being treated with fulvestrant. Customers should be informed that fulvestrant will increase the apparent concentration of estradiol in women being treated with this drug. If treatment with fulvestrant has been altered or discontinued as a result of falsely elevated e

Identifiers

code_infoPart Number Elecsys Estradiol II : 03000079190; all lot numbers are affected.

Status history

No status changes recorded since RecallRadar first saw this recall on 2026-09-13 11:54 UTC. Current status: terminated.

Source

Official record: https://api.fda.gov/device/enforcement.json?search=recall_number:%22Z-1277-2016%22

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